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A recent UK study highlights that medical cannabis can significantly improve health-related quality of life, anxiety, and sleep quality for patients with chronic conditions. The research also noted a reduction in opioid use among cannabis patients, particularly those prescribed dried cannabis flowers over tinctures and lozenges.
Understanding the Complexity of Cannabis Research
Cannabis, a plant with over 400 chemical compounds, poses a challenge for researchers due to its variability. Over 100 of these compounds have known medical effects, varying with strain, cultivation, processing, and consumption methods. This complexity often results in observational studies that capture a broad spectrum of substances, while controlled studies tend to isolate specific components, missing out on the interaction of multiple compounds.
This study, however, took a unique approach by focusing on specific regimens of medical cannabis, providing more detailed insights into its effects on patient well-being. The findings suggest that the type and form of cannabis prescribed can influence the extent of clinical improvements.
Key Findings: Dried Cannabis Flowers vs. Sublingual Options
Patients using dried cannabis flowers, typically consumed by smoking or vaporizing, showed more significant improvements compared to those using sublingual forms like tinctures and lozenges. While both groups saw benefits, the improvements were more pronounced among the flower users.
Notably, even patients who used a combination of both dried flowers and sublingual options experienced similar positive outcomes. However, those exclusively using sublinguals had less substantial improvements, though still better than their baseline conditions.
Side Effects and Patient Adaptation
While around 20% of patients reported side effects, most were mild to moderate, including fatigue, excessive sleepiness, dry mouth, lethargy, and headaches. Only one of the 1,378 participants experienced a single episode of psychosis. Patients already familiar with cannabis experienced fewer side effects compared to new users.
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